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Sex Linkage Sex Linkage Sex linkage applies to genes that are located on the sex chromosomes. These genes are considered sex-linked because their expression and inheritance patterns differ between males and females. While sex linkage is not the same as genetic linkage , sex-linked genes can be genetically linked see bottom of page. Sex Chromosomes Sex chromosomes determine whether an individual is male or female. In humans and other mammals, the sex chromosomes are X and Y. Females have two X chromosomes, and males have an X and a Y. Non-sex chromosomes are also called autosomes.Sex linked genes are genes that are in the sex chromosomes and that are therefore inherited differently between males and females. In mammals, where the. Genes that are carried by either sex chromosome are said to be sex linked. Men normally have an X and a Y combination of sex chromosomes, while women. Sex-linked diseases are passed down through families through one of the X Dominant inheritance occurs when an abnormal gene from one...the end of the story look at the video above ↑ ↑ ↑